Unusually Resistant Post-Traumatic Uveitis with High Serum ACE—An Occult Ocular Sarcoidosis?

Abstract

Purpose: The initiation of acute anterior uveitis following non-penetrating trauma comprises a defined clinical entity although its pathophysiology is not yet completely understood. Design and Methods: Case presentation. Results: We present two cases of young boys in whom a first episode of resistant anterior uveitis developed following relatively minor non penetrating ocular injury. Further investigation revealed high levels of serum ACE in both cases. Conclusion: To the best of our knowledge there are no previous published reports implicating minor ocular trauma in precipitating a first episode of uveitis associated with high serum ACE. A better understanding of the pathophysiology may provide insight into alternative treatments.