ABSTRACT
Purpose
To report a histopathology and molecular biology study of an eyeball of a case of acute retinal necrosis (ARN).
Methods
Histopathology, immunohistochemistry and molecular biology of an enucleated globe of acute retinal necrosis 6 years after the onset of ARN.
Results
Histopathology showed persistence of chronic inflammatory cells with herpes virus inclusion body. Semi nested polymerase chain reaction showed varicella zoster virus.
Conclusions
Chronic inflammatory cells and viral genome can be persistent even after 6 years after the onset of ARN.