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Original Articles

Histopathology and Molecular Biology Study of an Eyeball of a Case of Acute Retinal Necrosis

, MS, , MS, , MS, , PhD, , MS & , MS
Pages 1471-1474 | Received 29 Dec 2020, Accepted 13 Feb 2021, Published online: 18 Mar 2021
 

ABSTRACT

Purpose

To report a histopathology and molecular biology study of an eyeball of a case of acute retinal necrosis (ARN).

Methods

Histopathology, immunohistochemistry and molecular biology of an enucleated globe of acute retinal necrosis 6 years after the onset of ARN.

Results

Histopathology showed persistence of chronic inflammatory cells with herpes virus inclusion body. Semi nested polymerase chain reaction showed varicella zoster virus.

Conclusions

Chronic inflammatory cells and viral genome can be persistent even after 6 years after the onset of ARN.

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