How Traumatic is Intravitreal Ozurdex Injection?

ABSTRACT

Background

This study intended to illustrate a rare case of pyogenic granuloma (PG) in retinal vein occlusion (RVO) patient after dexamethasone (DEX) implant therapy.

Case Description

A 58-year-old female who underwent DEX implant therapy a month ago due to RVO presented with a mass in her right eye. Anterior segment analysis revealed a slowly enlarging, round, fleshy vascular mass indicating PG located at the injection site. Although surgical excision was planned, because of the Covid-19 pandemic, a patient could not come for surgery. Ocular examination revealed a spontaneous PG disappearance three months later. A small mass could, however, be detected using an anterior segment optical coherence tomography.

Conclusion

While superficial PG regression can only be observed by slit-lamp biomicroscopy, extensive root ingrowth can be clearly differentiated by anterior segment optical coherence tomography. Besides, depending on the nature, size, location, and associated symptoms, some PG may be left to regress but with close monitoring.

KEYWORDS:

• Anterior segment OCT
• anterior segment photography
• retinal vein occlusion
• Ozurdex
• pyogenic granuloma

Declaration of interest

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.

Informed consent

Written informed consent was obtained from the patient for the publication of the case report and the accompanying images.

Additional information

Funding

This research has earned no particular grant from any state, commercial or non-profit funding agency.