Evaluation of Retinal Microvascular Perfusion Changes in Patients with Celiac Disease

ABSTRACT

Purpose

We aimed to determine whether there are retinal microvascular changes in patients with celiac disease (CD).

Methods

A total of 30 patients with CD (group 1) and 30 healthy controls (group 2) were included in this study. AngioVue optical coherence tomography angiography (OCTA) device was used to evaluate the retinal microvascular structure.

Results

Some of the values of both optic nerve head (ONH) vessel density (VD) and radial peripapillary capillary VDs were found to be significantly lower in group 1 than in group 2. These 2 groups were similar except for one of the parameters of superficial capillary plexus VD (SCP-VD), whereas it was found that deep capillary plexus VD (DCP-VD) was lower in group 1 than in group 2 except for the foveal area.

Conclusion

It was determined that some VDs obtained from the ONH and DCP-VD obtained from most areas of the macular region were significantly lower.

KEYWORDS:

• Celiac disease
• optical coherence tomography angiography
• vascular density
• superficial capillary plexus
• deep capillary plexus

Acknowledgments

The authors thank Yeşim Arıkan Çelik for all images.

Declaration of Interest

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.

Additional information

Funding

No funding was required for the study.