ABSTRACT
Purpose
Frosted branch angiitis (FBA) is a rare form of retinal vasculitis. Four case series and an extensive literature review of 236 cases were conducted to clarify the characteristics of this rare condition.
Methods
Case series and literature review.
Results
An analysis of the reported cases revealed that a majority (54.6%) developed FBA in the presence of an underlying disease, with recurrence and complications requiring surgical intervention being rare. The frequency of bilateral occurrence (55.0%) and prevalence in female patients (45.0%) were noted to be lower than previously reported.
Conclusion
In general, idiopathic FBAs are more likely to be bilateral and diagnosed at a younger age than secondary FBAs. In idiopathic FBA, fundus involvement is more generalized, exudates tend to be more translucent, and extensive retinal hemorrhage tends to be less frequent. However, there were no differential characteristic fundus features that clearly distinguished idiopathic FBA from secondary FBA.
Acknowledgments
This work was supported by an Inha University Hospital research grant.
Disclosure statement
No potential conflict of interest was reported by the author(s).
Authors’ contributions
KL, SJ, and HSC participated in data analysis and drafting of the manuscript. HSC participated in the patient management. All authors have read and approved the final manuscript.
Supplementary material
Supplemental data for this article can be accessed online at https://doi.org/10.1080/09273948.2022.2148112