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Biophotonics

Towards a FAST-CARS anthrax detector: CARS generation in a DPA surrogate molecule

, , , &
Pages 2361-2368 | Received 23 Mar 2003, Published online: 24 Apr 2008
 

Abstract

Coherent anti-Stokes Raman spectroscopy (CARS) has been investigated as a detection method for the identification of dipicolinic acid (DPA), a marker molecule for bacterial spores of anthrax. The laser dye molecule DCM was used as a surrogate molecule for DPA. In preliminary experiments, a molecular sensitivity was achieved in DCM that is projected to be sufficient to detect the DPA in bacterial spore clumps as small as 5.5 μm in diameter, small enough to be of interest in practical detection scenarios.

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