Improvement of hyperandrogenism, oligo-ovulation, and ovarian morphology in a patient with polycystic ovary syndrome: possible role of ovarian wedge resection

Abstract

Polycystic ovary syndrome (PCOS) is an endocrinological abnormality which typically presents as hormones disorder and/or infertility. It has received more and more attention in recent years though its pathogenesis is still unclear. Ovarian mucinous adenoma is a rarely pathological type which generates from epithelial cell of ovary. Here we present a patient with PCOS and ovarian mucinous tumor (occasionally discovered by cesarean section) receiving a complete relief after benign ovarian tumor excision. In this case, tumor excision played as a partial resection of ovary which might result in the normalized concentration level of hormones and morphology of ovary. This report suggests that therapeutic strategies for PCOS should be considered more carefully and individually.

Chinese abstract

多囊卵巢综合征（PCOS）是一种内分泌异常疾病, 通常表现为激素紊乱和/或不孕。尽管其发病机制尚不清楚, 但近年来PCOS受到越来越多的关注。卵巢粘液腺瘤是一种罕见的病理类型, 由卵巢上皮细胞来源。在这里, 我们介绍了一例PCOS合并卵巢粘液腺瘤患者（剖宫产偶然发现）在卵巢良性肿瘤切除术后, PCOS症状得到完全缓解。在这个病例里, 作为卵巢部分切除的肿瘤切除可能造成激素浓度水平和卵巢形态的正常化。本例报告表明, PCOS的治疗策略应更为仔细的权衡和个体化考虑。

Keywords:

• PCOS
• mucinous adenoma
• ovarian partial resection
• hyperandrogenism

Acknowledgments

We would like to give our thanks to the patient for her cooperation in clinical data. The study was supported by the National Natural Science Foundation of China 81601261, Henan provincial science and technology research projects 201303165 and 144200510027.

Disclosure statement

All authors declare that there are no conflicts of interest.