Paraganglioma in pregnancy: interdisciplinary management during pregnancy

Abstract

Paragangliomas are tumors that originate from the extra-adrenal neural crest, the incidence of which during pregnancy is not more than two to eight cases per million people per year and are known to be highly morbid. The purpose of this report is to describe the experience and results obtained during management of a primigravida diagnosed with paraganglioma on week 21.2 and received both medical and surgical management with good maternal and perinatal outcomes. This case report evidences the importance of practicing interdisciplinary management of patients with clinical suspicion of paragangliomas or pheochromocytomas during pregnancy at high-complexity centers even in a medium-income country.

摘要

副神经节瘤是起源于肾上腺外神经鞘的肿瘤, 其妊娠期发病率不超过百万分之二到八, 被认为是非常罕见的。本病例报告的目的是：描述一在孕21.2周诊断为副神经节瘤的初产妇, 在妊娠期治疗过程中所获得的经验和结果, 以及有良好母婴结局的内、外科治疗。本病例报告表明, 即使在中等收入国家, 妊娠期对临床怀疑副神经节瘤或嗜铬细胞瘤的患者在妊娠期进行跨学科管理是很重要的。

The Chinese abstracts are translated by Prof. Dr. Xiangyan Ruan and her team: Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing 100026, China.

Keywords:

• Pheochromocytoma
• paraganglioma
• pregnancy
• hypertensive disorders
• metanephrines

Disclosure statement

No potential conflict of interest was reported by the authors.