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Research Article

Risk factors of osteoporosis and osteopenia in postmenopausal women based on the L2–L4 BMD T score of the lumbar spine: a study in Iran

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Article: 2205959 | Received 26 Oct 2021, Accepted 18 Apr 2023, Published online: 03 May 2023
 

Abstract

Objective

To determine the risk factors of osteoporosis and osteopenia of the spine in postmenopausal women.

Method

An analytical cross-sectional study was performed on postmenopausal women. The T-score of the lumbar spine (L2–L4) was measured by densitometry and compared between osteoporotic, osteopenia, and normal women.

Results

One thousand three hundred fify-nine postmenopausal women were evaluated. The prevalence of osteopenia and osteoporosis was 58.2% and 12.8% respectively. Age, BMI, parity, total breastfeeding years, dairy use, calcium-D supplements, and regular exercise were significantly different in women with osteoporosis, osteopenia, and normal women. Ethnicity, diabetes, and previous fracture history were only other among women with osteoporosis (not osteopenia) and normal women. For osteopenia of the spine, age [AOR 1.08 (1.05–1.11; p < .001)] was the risk factor, and BMI = >30 [AOR 0.36 (0.28–0.58; p < .001)] and BMI 25–<30 [AOR 0.55 (0.34–0.88; p = .012)] were protective factors. Hyperthyroidism (AOR 23.43, p = .010), Kurdish ethnicity (AOR 2.96, p = .009), not having regular exercise (AOR 2.22, p = .012), previous fracture history (AOR 2.15, p = .041)], and age (AOR 1.14, p < .001)], were risk factors for osteoporosis, while BMI ≥30 [AOR 0.09, p < .001], BMI 25–<30 [AOR 0.28, p = .001], and diabetes [AOR 0.41, p = .038] were protective factors for osteoporosis of the spine.

Conclusion

Hyperthyroidism, low BMI <25, parity ≥ 6, Kurdish ethnicity, not having regular exercise, history of previous fracture, and age, were risk factors for osteoporosis of the spine respectively, while low BMI and age were risk factors for osteopenia.

Disclosure statement

None.

Additional information

Funding

The author(s) reported there is no funding associated with the work featured in this article.