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Articles

A new algorithm for detection of epileptic seizures based on HRV signal

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Pages 251-265 | Received 28 Dec 2012, Accepted 01 Aug 2013, Published online: 23 Jan 2014
 

Abstract

Epilepsy is one of the most frequent neurological disorders. In a significant number of cases, skilled professionals carry out the detection of the epileptic seizures manually. This necessitates automated epileptic seizure detection. Many researchers have presented computational methods for detecting epileptic seizures based on electroencephalogram signals. In this article, we propose a novel and efficient algorithm for detecting the presence of epileptic seizures in heart rate variability (HRV). This algorithm includes feature extraction and classification. Ten features include time and frequency domain analysis and nonlinear features extracted from one-lead electrocardiogram signal of epileptic patients. Extracted features were used as the input of an artificial neural network, which provides the final classification of the HRV segments (existence of epileptic seizure or not). Multilayer perceptron neural networks with different number of hidden layers and five training algorithms were designed. The results show sensitivity, specificity and accuracy of 88.66%, 90% and 88.33%, respectively, in secondary generalised and 83.33%, 86.11% and 84.72%, respectively, in complex partial seizures. The experimental results portray that the proposed algorithm efficiently detects the presence of epileptic seizure in HRV signals and showed a reasonable accuracy in detection.

Acknowledgements

The authors express their deepest gratitude to Mr Mohammad Karimi Moridani for his sincere and ongoing support at different stages of developing this paper.

Notes

Additional information

Funding

Funding
This work is partially funded by the European Project EPILEPSIAE EU FP7 [grant number 211713] and ICIS project CENTRO-07-0224-FEDER-002003.

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