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AIDS Care
Psychological and Socio-medical Aspects of AIDS/HIV
Volume 19, 2007 - Issue 1
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Original Articles

HIV vaccine trial preparedness among Spanish-speaking Latinos in the US

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Pages 52-58 | Published online: 10 Apr 2007
 

Abstract

Latinos are under-represented in HIV/AIDS medical research in the US. Although they are disproportionately impacted by HIV/AIDS, Latinos may be reluctant to participate in HIV vaccine trials. Three focus groups were conducted with 32 Spanish-speaking Latinos recruited from two community-based healthcare organizations in Los Angeles, California. A qualitative focus group interview guide was developed to explore concerns, motivators and intentions in regard to participation in HIV vaccine trials. Mistrust and fear of government emerged as important themes related to reluctance to participate in an HIV vaccine trial. Specific concerns regarding trial participation included: (1) fear of vaccine-induced HIV infection, (2) physical side effects, (3) stigma and (4) false-induced HIV-positive test results and their social repercussions. Motivators for enrolling in an HIV vaccine trial included: (1) incentives, (2) convenience of participating in a study, (3) sufficient and appropriate study information, (4) personal benefits and (5) altruism. Interventions to facilitate participation by Latinos in HIV vaccine trials should address mistrust and fear of government-sponsored HIV/AIDS medical research, increase access to and convenience of clinical trials, address fear of vaccine-induced infection, combat HIV/AIDS stigma and raise awareness of the relevance of HIV/AIDS to Latino communities.

Acknowledgments

This research was supported by the Universitywide AIDS Research Program through a grant to the UCLA California AIDS Research Center (CC99-LA-002) and the UCLA AIDS Institute and Pallotta Teamworks AIDS Vaccine Rides and by grant P30MH58107 from the National Institutes of Mental Health.

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