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AIDS Care
Psychological and Socio-medical Aspects of AIDS/HIV
Volume 21, 2009 - Issue 11
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ORIGINAL ARTICLES

The risk of HIV and HCV infections among injection drug users in northeast India

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Pages 1420-1424 | Received 04 Jul 2008, Published online: 28 Oct 2009
 

Abstract

Injection drug users (IDUs) and their associated risk behavior are responsible for driving the human immunodeficiency virus (HIV) epidemic in northeast India. So a group of IDUs from two northeastern states (Mizoram and Nagaland) of India were studied to find the prevalence of HIV, co-infection with hepatitis C virus (HCV), hepatitis B virus (HBV), and associated risk behaviors. Out of the 400 IDUs enrolled, 398 consented for HIV, HCV, and hepatitis B surface antigen (HbsAg) test. Of them, 10.8% were HIV-1 antibody positive, 47.8% had HCV antibody, and 3.8% had detectable HBsAg. Among the HIV infected subjects, 79.1% were co-infected with HCV and 6.9% had triple infection. Heroin users showed a higher association with HIV (OR = 7.3, 95% CI: 2.5–21.5, p=0.0003) and HCV infection (OR = 7.6, 95% CI: 3.5–16.6, p<0.0001) than Spasmo-proxyvon (dextropropoxyphene, a synthetic opiod analgesic). In summary, apart from the known risk variables among IDUs, type of injecting drugs also influences the HIV/HCV transmission pattern among the IDUs.

Acknowledgements

The study was carried out from the ICMR Task-force project, Indian Council of Medical Research (ICMR), Goverment of India.

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