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AIDS Care
Psychological and Socio-medical Aspects of AIDS/HIV
Volume 32, 2020 - Issue 7
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Articles

Oral environment and taste function of Japanese HIV-infected patients treated with antiretroviral therapy

ORCID Icon, , , , , , , , , , , & show all
Pages 829-834 | Received 08 Jan 2019, Accepted 15 Jul 2019, Published online: 19 Aug 2019
 

ABSTRACT

The aim of the study was to evaluate the oral environment and the taste function of Japanese HIV-infected patients treated with antiretroviral therapy. Their median age of 73 patients taking anti-HIV drugs was 46 years. The median period of taking anti-HIV drugs was 30 months. The oral condition was evaluated by measurement of oral moisture, amount of saliva secretion, the number of oral bacteria, presence of oral candida, a taste test, and the number of missing teeth. The levels of oral moisture and secreted saliva were significantly lower in the HIV-infected group than in the healthy volunteer (control) group. The HIV-infected group showed a more robust decrease in taste sensation than the control group. The number of missing teeth was significantly higher in the HIV-infected group than in the control group. Furthermore, all of the evaluated oral conditions were worse in the HIV-infected patients whose CD4+ T lymphocyte counts were less than 500/mm3 than in the control group. It became clear that the patients taking anti-HIV drugs, especially the CD4+ count < 500/mm3 group, had a deteriorated oral environment and dysgeusia, suggesting that the management of oral hygiene is necessary to maintain oral health, which leads to systemic health.

Acknowledgments

This research was in part supported by Research Grants received from Hiroshima Prefecture (2014–2016) for the construction of dental practice network for HIV-infected people in Chugoku and Shikoku Block in Japan.

Disclosure statement

No potential conflict of interest was reported by the authors.

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