Reproductive and sexual health knowledge, experiences, and milestones in young adults with life-long HIV

ABSTRACT

Reproductive and sexual health outcomes of adults with perinatal human immunodeficiency virus (PHIV) have not been well-characterized. This prospective cross-sectional study of 35 adult persons living with HIV (PLWH) from early life and 20 matched HIV-negative controls assessed quality of life, depressive symptoms, HIV transmission knowledge, and sexual/reproductive behaviors through self-report questionnaires. PLWH scored significantly worse than controls on depressive symptoms (p = 0.04) and two of six quality of life domains (p = 0.03, p = 0.0002). In contrast, PLWH scored significantly higher on transmission knowledge in the context of family planning (p = 0.002). PLWH were more likely to learn about sex from healthcare providers (p = 0.002) and were more confident in their sexual/reproductive health knowledge (p < 0.05). Both groups reported inconsistent condom use, but PLWH were more likely to have planned pregnancies (p = 0.005) and to share pregnancy planning with their partners (p < 0.05). Despite the challenges of living with a chronic stigmatized condition, adults with PHIV were knowledgeable about HIV transmission and family planning and demonstrated sexual practices and reproductive outcomes similar to age-matched controls. However, sub-optimal rates of viral suppression, inconsistent condom use, and the psychosocial impact of living with HIV continue to require the attention of healthcare provides for young adults with PHIV.

KEYWORDS:

• Perinatal HIV
• reproductive outcomes
• sexual transmission

Acknowledgements

The authors wish to thank the work of John Crissey for the development of the secure online questionnaire platform, and we also thank the research participants for their time and willingness to share their personal experiences.

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

This research was support by the Intramural Research Program of the National Institute of Allergy and Infectious Diseases (Division of Intramural Research, National Institute of Allergy and Infectious Diseases).