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AIDS Care
Psychological and Socio-medical Aspects of AIDS/HIV
Volume 36, 2024 - Issue 3
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Research Article

Health disparities in mortality among individuals with HIV-associated dementia in South Carolina

ORCID Icon, , , , , , & show all
Pages 291-295 | Received 05 Jul 2022, Accepted 30 May 2023, Published online: 08 Jun 2023
 

ABSTRACT

HIV disproportionately affects the South compared to other regions of the US. Some people living with HIV (PLWH) may acquire HIV-associated neurocognitive disorders (HAND), of which HIV-associated dementia (HAD) is the most severe form. This study aimed to examine the disparities in mortality among individuals with HAD. Data were obtained from the South Carolina Alzheimer’s Disease and Related Dementias Registry from 2010 to 2016 (HAD: n = 505; N = 164,982). Logistic regression and Cox proportional hazards models were used to determine mortality related to HIV-associated dementia and potential sociodemographic differences. Adjusted models controlled for age, gender, race, rurality, and place of diagnosis. Individuals diagnosed in a nursing facility were three times more likely to die with HAD compared to those diagnosed in the community (OR: 3.25; 95% CI: 2.08–5.08). Black populations were more likely to die with HAD compared to White populations (OR: 1.52; 95% CI: 0.953-2.42). Disparities in mortality among patients with HAD were found in place of diagnosis and by race. Future research should determine if mortality among individuals with HAD were as a result of HAD or non-HIV related decline.

Disclosure statement

No potential conflict of interest was reported by the author(s).

Additional information

Funding

This research was supported by the NIA-funded Carolina Center on Alzheimer’s Disease and Minority Research (CCADMR) #5P30AG059294-02.National Institute of Aging

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