Oral calcitriol in the treatment of scleroderma 'en coupe de sabre'

Abstract

A 20-year-old girl presented with a rapidly enlarging band of linear scleroderma involving the forehead and frontal scalp with linear alopecia. The parietal skull contained an arciform bone depression with mild thinning of the hair. Previous treatment with hydroxychloroquine and systemic steroids had failed to arrest the progression of the plaque. Treatment with calcitriol (Rocaltrol®, Roche) 0.75 m g/day for 12 months produced a prompt resolution of the perilesional erythema, gradual thinning of the band of scleroderma and partial hair regrowth. ( J Dermatol Treat (2000) 11: 207-208)

• Alopecia Calcitriol Vitamin D Morphea Scleroderma