Severe erythema nodosum due to Behçet's disease responsive to erythromycin

Abstract

A patient with severe erythema nodosum due to Behçet's disease is reported on here. Erythema nodosum lesions did not respond to classical treatments; however, they cleared after erythromycin treatment, which was prescribed for the treatment of coincidental erythrasma. Erythromycin treatment appears to be an effective treatment option in erythema nodosum. The hypothetical anti‐inflammatory effects of erythromycin, besides its antibiotic properties, are reviewed and discussed to explain such a clinical improvement.

• Behçet's disease
• Erythema nodosum
• Erythromycin
• Macrolide
• Treatment