d‐penicillamine‐induced pemphigus successfully treated with combination therapy of mizoribine and prednisolone

K Sugita Department of Dermatology, University of Occupational and Environmental Health, Kitakyushu, Japan

H Hirokawa Department of Dermatology, University of Occupational and Environmental Health, Kitakyushu, Japan

K Izu Department of Dermatology, University of Occupational and Environmental Health, Kitakyushu, Japan

Y Tokura Department of Dermatology, University of Occupational and Environmental Health, Kitakyushu, JapanCorrespondencek‐[email protected]‐u.ac.jp

Abstract

A 63‐year‐old woman had d‐penicillamine‐induced pemphigus with a high index value of circulating autoantibodies against desmoglein 1. Because of the lack of response to prednisolone monotherapy, the patient was treated with a combination therapy of mizoribine and low‐dose prednisolone. The skin eruption was improved by this combination with a declined value of circulating anti‐desmoglein 1 antibody. Currently, a remission of 2 months has been achieved, and prednisolone could be tapered.

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d‐penicillamine‐induced pemphigus successfully treated with combination therapy of mizoribine and prednisolone

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d‐penicillamine‐induced pemphigus successfully treated with combination therapy of mizoribine and prednisolone

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