Topical streptococcal preparation, OK‐432, for atopic dermatitis

Abstract

Effective treatment of atopic dermatitis (AD) may in some cases prove quite difficult. OK‐432, prepared from the penicillin‐treated Su strain of type III Group A Streptococcus pyogenes, has been shown to be effective for treating not only cancer but verruca vulgaris as well, suggesting this agent to create the Th1 pathway through IL‐12 induction. Four AD patients consented to trial use of the OK‐432 ointment. OK‐432 was found to bring about complete cure in the present four cases. Based on results from its use, OK‐432 may be concluded to be highly effective for treating AD.

• Atopic dermatitis
• OK‐432
• Streptococcus pyogenes