Disseminated classic Kaposi's sarcoma. Two cases with excellent response to pegylated liposomal doxorubicin

Iria Castiñeiras Department of Dermatology, Hospital Juan Canalejo, La Coruña, SpainCorrespondence[email protected]

Manuel Almagro Department of Dermatology, Hospital Juan Canalejo, La Coruña, Spain

Jesús Rodríguez‐Lozano Department of Dermatology, Hospital Juan Canalejo, La Coruña, Spain

Beatriz Fernández‐Jorge Department of Dermatology, Hospital Juan Canalejo, La Coruña, Spain

Sabela Paradela Department of Dermatology, Hospital Juan Canalejo, La Coruña, Spain

Jesús Del Pozo Department of Dermatology, Hospital Juan Canalejo, La Coruña, Spain

Eduardo Fonseca Department of Dermatology, Hospital Juan Canalejo, La Coruña, Spain

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Abstract

Pegylated liposomal doxorubicin (PLD) is usually used in disseminated HIV‐related Kaposi's sarcoma (KS). It is the first‐line treatment or second‐line therapy in patients who do not tolerate or do not respond to polychemotherapy since 1995, when it was approved by the FDA. We report two cases of disseminated classic KS not associated with immunosuppression in which HHV‐8 infection was demonstrated. They showed an excellent response to PLD, with good tolerance and an absence of side effects.

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Disseminated classic Kaposi's sarcoma. Two cases with excellent response to pegylated liposomal doxorubicin

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Disseminated classic Kaposi's sarcoma. Two cases with excellent response to pegylated liposomal doxorubicin

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