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Abstract
Background: There have been few studies regarding the results of the Korean standard patch test.
Objectives: The purpose of this study was to analyze the type and frequency of common contact allergens in Korea and to compare the results with those of previous reports.
Methods: From June 2009 to June 2014, 330 patients with suspected allergic contact dermatitis who visited our clinic were tested using the Korean standard patch test.
Results: The highest sensitization rate was found for nickel sulfate (47.58%). There was a significant gender difference in the prevalence of sensitization to nickel sulfate (OR = 2.41, p = .0004) and wool alcohol (OR = 2.85, p = .0358). Higher sensitization to nickel sulfate (OR = 1.18, p = .0159), 4-phenylenediamine (OR = 1.23, p= .003), tixocortol-21-pivalte (OR 1.48, p = .0212) and lower sensitization to thimerosal (OR = 0.77, p = .0023) were associated with increasing age. Patients with allergic contact dermatitis on the scalp had a significantly higher risk of sensitization to 4-phenylenediamine (OR = 3.07, p = .0013). Patients with allergic contact dermatitis on the hands had significantly higher risks of sensitization to wool alcohol (OR = 3.44, p = .0083), formaldehyde (OR = 2.52, p = .0178), and colophony (OR = 2.05, p = .0499).
Conclusions: These results demonstrate trends in patch test results in Korea and the basis for the presumption of the route of allergen exposure.
Disclosure statement
Authors declare no conflicts of interest.
Funding
This study was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIP) [No.2016R1C1B1008288].