A novel plant-derived compound is synergistic with 5-fluorouracil and has increased apoptotic activity through autophagy in the treatment of actinic keratoses

Cameron E. Westa Genzada Pharmaceuticals USA, Inc., Sterling, KS, USAView further author information

Shawn G. Kwatrab Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD, USACorrespondence[email protected]

https://orcid.org/0000-0003-3736-1515 View further author information

Justin Choic University of Illinois College of Medicine, Chicago, IL, USAView further author information

Daniel Von Hoffd Translational Genomics Research Institute (TGEN), Phoenix, AZ, USAView further author information

Laurence Boothe Department of Biochemistry and Molecular Biology, Virginia Commonwealth University, Richmond, VA, USAView further author information

Paul Dente Department of Biochemistry and Molecular Biology, Virginia Commonwealth University, Richmond, VA, USAView further author information

"A novel plant-derived compound is synergistic with 5-fluorouracil and has increased apoptotic activity through autophagy in the treatment of actinic keratoses." Journal of Dermatological Treatment, 33(1), pp. 590–591

Disclosure statement

Dr. Von Hoff is a consultant and advisory board member for Genzada Pharmaceuticals. Dr. West is a paid officer and Board member of Genzada Pharmaceuticals. Dr. Kwatra is an advisory board member for Genzada Pharmaceuticals. Dr. Dent is a consultant and advisory board member for Genzada Pharmaceuticals.

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These studies were supported by funding from Genzada Pharmaceuticals USA, Inc.

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A novel plant-derived compound is synergistic with 5-fluorouracil and has increased apoptotic activity through autophagy in the treatment of actinic keratoses

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A novel plant-derived compound is synergistic with 5-fluorouracil and has increased apoptotic activity through autophagy in the treatment of actinic keratoses

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