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Summary
No significant change in the serum-protein concentration or composition was observed among the AET-950 and 950 r-IBM mice. A decrease in the albumin concentration and an increase in the globulin concentration was seen after 950 r only. Associated with the secondary loss in body-weight among the 950 r-RBM mice is a decrease in the albumin/globulin ratio, extending from the second through the seventh weeks, and caused by an increase in the lipo-protein concentration and a decrease in the albumin concentration.