X-radiation and 5-hydroxytryptamine-content in the Brain of Rats and Mice: International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine: Vol 6, No 3

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Summary

Whole-body x-irradiation with high doses produces an increase in the 5-hydroxytryptamine-content in the brain of normal rats and mice. This effect was obtained with smaller doses only in adrenalectomized rats. Shielding of the head or body did not suppress this phenomenon. The same holds true of pre-treatment with iproniazid or reserpine.

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X-radiation and 5-hydroxytryptamine-content in the Brain of Rats and Mice

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