The Effect of Pre-irradiation Growth Conditions on the Relative Radiosensitivities of Mammalian Cells at Low Oxygen Concentrations

Summary

The value of K depends on the pre-irradiation growth conditions of the mouse Ehrlich ascites tumour. Cells were grown either in vivo or in vitro but were irradiated and assayed in vitro. K was 1·8 times greater for cells grown in vitro, demonstrating that K is not invariant for mammalian cells, nor even for the same cell-line.