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Original Article

Comparison of Radiation-induced Radical Yields in Short Peptides and Constituent Amino Acids by Detection of Trapped Oxygen Isotope 18O

Pages 93-97 | Received 18 Mar 1983, Accepted 06 Jun 1983, Published online: 03 Jul 2009
 

Summary

This report compares the radiosensitivity of small polypeptides and constituent isolated amino acids using a novel technical approach. The radiation-induced oxygen isotope 18O trapping was measured by means of nuclear reactions. Most of the peptides reveal a higher sensitivity than a mixture of their constituent amino acids. This observation can be rationalized with a simple model which implies intramolecular energy transfer.

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