Effects of Age, Sex and Diagnostic X-rays on Chromosome Damage

Amos Norman Laboratory of Biomedical and Environmental Sciences, University of California, Los Angeles, California, 90024, U.S.A.

Sachiko Cochran Department of Radiation Oncology, University of California, Los Angeles, California, 90024, U.S.A.

Doris Bass Department of Radiological Sciences, University of California, Los Angeles, California, 90024, U.S.A.

Denise Roe Jonsson Comprehensive Cancer Center, University of California, Los Angeles, California, 90024, U.S.A.

Summary

The frequency of micronuclei assayed in lymphocytes obtained from 73 young adults increases significantly with the age, but not the sex, of the donor. The dose of medical X-rays absorbed by the lymphocytes in the 2 years before the examination has no significant effect on micronucleus frequency, provided the data are adjusted for age. However, a small significant increase in frequency is associated with X-ray examinations that involve the injection of contrast media into the blood.

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Effects of Age, Sex and Diagnostic X-rays on Chromosome Damage

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