Effect of X-rays Alone or Combined with Diethylnitrosamine on Cancer Induction in Mouse Liver

J.R. Maisin Department of Biology, Centre d'Etude de l'Energie Nucléaire, B-2400, Mol, Belgium

L. De Saint-Georges Department of Biology, Centre d'Etude de l'Energie Nucléaire, B-2400, Mol, Belgium

M. Janowski Department of Biology, Centre d'Etude de l'Energie Nucléaire, B-2400, Mol, Belgium

M. Lambiet-Collier Department of Biology, Centre d'Etude de l'Energie Nucléaire, B-2400, Mol, Belgium

G. Mattelin Department of Biology, Centre d'Etude de l'Energie Nucléaire, B-2400, Mol, Belgium

Summary

The possible combined effects of the initiator diethylnitrosamine (DEN) with X-rays on cancer induction in infant C57BL/Cnb mice were evaluated. Preliminary data show that a dose of X-rays administered 7 days before a single injection of DEN was more effective in inducing liver nodules than when administered 7 days after DEN administration.

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Effect of X-rays Alone or Combined with Diethylnitrosamine on Cancer Induction in Mouse Liver

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Effect of X-rays Alone or Combined with Diethylnitrosamine on Cancer Induction in Mouse Liver

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