Modeling an irritant gas plume for epidemiologic study

Abstract

Plume dispersion modeling systems are often used in assessing human exposures to chemical hazards for epidemiologic study. We modeled the 2005 Graniteville, South Carolina, 54,915 kg railcar chlorine release using both the Areal Locations of Hazardous Atmospheres and Hazard Prediction and Assessment Capability (HPAC) plume modeling systems. We estimated the release rate by an engineering analysis combining semi-quantitative observations and fundamental physical principles. The use of regional meteorological conditions was validated by comparing concentration estimates generated by two source-location weather data-sets. The HPAC model estimated a chlorine plume with 20 ppm outdoor concentrations up to 7 km downwind and 0.25 km upwind/downgrade. A comparative analysis of our two models showed that HPAC was the best candidate for use as a model system on which epidemiologic studies could be based after further model validation. Further validation studies are needed before individual exposure estimates can be reliable and the chlorine plume more definitively modeled.

Keywords:

• atmospheric
• agriculture
• risk
• epidemiology

Acknowledgements

We acknowledge Ronald G. Meris, Chief of the Reachback Analysis Branch of the Defense Threat Reduction Agency (DTRA), for his scientific review and helpful commentary on this manuscript.

Additional information

Funding

This work was supported by the National Institute of Environmental Health Sciences [5R01ES015532-05].