Triaxial accelerometer output predicts oxygen uptake in adults with Down syndrome

Abstract

Purpose

This study examined if the relationship between the rate of oxygen uptake (V̇O₂) and output from hip-and wrist-worn accelerometers differs between adults with and without DS, and evaluated the accuracy of accelerometer output in estimating V̇O₂.

Materials and methods

Sixteen adults with DS (10 men) and 19 adults without DS (10 men) performed 12 tasks including physical activities and sedentary behaviors. We measured V̇O₂ with portable spirometry and accelerometer output (vector magnitude [VM]) with hip- and wrist-worn accelerometers. We used multi-level regressions to predict V̇O₂ from VM, group, body mass index (BMI), age, height, weight, and sex. We evaluated prediction accuracy with absolute percent error and Bland-Altman plots.

Results

For both hip- and wrist-accelerometers, VM and group significantly predicted V̇O₂ (p ≤ 0.021). When BMI was added, BMI was a significant predictor but group was not. The final models included VM and BMI (p ≤ 0.001; R² = 0.78 and 0.57, for hip and wrist accelerometer model, respectively). Absolute error was greater for the wrist- than the hip-accelerometer model (wrist: 37.9 ± 38.1%; hip: 22.5 ± 27.4%).

Conclusions

Adults with DS have different V̇O₂ to VM responses, and this appears due to their higher BMI. Predictability of V̇O₂ from accelerometer output is better for hip- than wrist-worn accelerometers.

IMPLICATIONS FOR REHABILITATION

• Output from a triaxial accelerometer has high potential in predicting the energy expenditure and classifying the intensity of physical activity and sedentary behavior in adults with Down syndrome.

• Accuracy of predicting energy expenditure from accelerometer output is better for hip- than wrist-worn triaxial accelerometers.

• The development of appropriate rehabilitation interventions that include physical activity for improving health and function in adults with Down syndrome requires accurate assessments of physical activity levels.

Keywords:

• Disability
• physical activity
• sedentary behavior
• accelerometers
• measurement

Ethical approval

All procedures performed were in accordance with the ethical standards of our institutional review board and with the 1964 Helsinki declaration and its later amendments. Informed consent was obtained from all participants.

Author contributions

ATA contributed to study design, data collection, data processing, interpretation of data, and manuscript composition. PC contributed to data collection, data processing, and critical revision of the manuscript. SA contributed to conception and design of the study, data collection, data analysis, interpretation of data, and composition of the article. All authors approved the final version.

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

Funding for this study was provided by the I’m An Athlete Foundation and the Office of Research and Economic Development, Mississippi State University.