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Original Articles

Lymphocyte Migration Inhibition Response to Babesia bigemina Live and Dead Antigens

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Pages 187-193 | Received 05 Jun 1996, Accepted 07 Oct 1996, Published online: 11 Nov 2011
 

Abstract

Tewari, A.K., Sharma, N.N., Rao, J.R. and Mishra, A.K. 1996. Lymphocyte migration inhibition response to Babesia bigemina live and dead antigens. J. Appl. Anim. Res., 10: 187–193.

In bovine babesiosis caused by Babesia bigemina, the role of cell mediated immune response (CMIR) was assessed by lymphocyte migration inhibition test (LMIT) following immunisation with babesial dead antigens administered alone or in combination with immunomodulators and upon challenge exposure to live virulent B. bigemina. Parasite-specific LMIT response was detectable in components. The migration inhibition (MI) index peaked at 14 days following immunisation and the index was significantly high from day 7 to 28 upon virulent challenge.

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