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Abstract
Sumano, H., Ocampo, L. and Azuara, J. 1998. Antibacterial activity, pharmacokinetics and therapeutic efficacy in poultry of a new cephalosporin-fluoroquinolone (CQ) molecule. J. Appl. Anim. Res., 13: 169–178.
The present paper deals with some of the pharamcological features of a new antibacterial drug, based on the coupling of a cephalosporanic and a fluoroquinolone group, code-named as CQ, including its comparative antibacterial potency, its pharmacokinetic features in poultry and clinical efficacy under controlled conditions and its comparative performance with enrofloxacin, against a field outbreak of chronic respiratory disease in broilers. Results suggest that the outstanding potency and clinical efficacy of this novel antibacterial merit further studies tc define other key pharmacological features, such as toxicology, drug residue kinetics and mechanism of action.