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Abstract
Rashwan, S. M., Al-Khalaf, H. N., Al-Hammad, M. I., Azab, A. H., Moustafa, M. H. and Diallo, A. 2000. Production and efficacy of peste des petits ruminants vaccine 75/1 in the Kingdom of Saudi Arabia. J. Appl. Anim. Res., 8: 225–231.
A freeze dried live attenuated vaccine against peste des petits ruminants (PPR) infection was prepared by growing an attenuated PPR strain 75/1 in vero cell culture. The produced vaccine batch that had a titre of 2x6.3 log 10 TCID50/100 dose was safe and potent. The mean titre of PPRV-neutralizing antibodies was 2.2 log 10 at the 21st day post-vaccination. The vaccine was thermostable when stored at 4C for 360 days. The reconstituted vaccine was still within the recommended titre after keeping at 20C for 8 hours, 37C for 4 hours and 45C for 1 hour.
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