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Abstract
Elsa, A.T., Osunkwo, U.A. and Onyeyili, P.A. 2003. Effect of chronic guanethidine treatment of amylobarbitone—induced anaesthesia. J. Appl. Anim. Res., 24: 101–104.
The effect of chronic treatment with guanethidine on the pattern of amylobarbitone induced anaesthesia in adult rabbits was studied to find out whether chemical sympathectomy influences barbiturate anaesthesia. The onset and duration of amylobarbitone induced anaesthesia decreased linearly (P<0.05), when treated with 2.5 or 5.0 mg/kg body weight guanethidine. Thus, guanethidine treatment may enhance induction but decrease duration of amylobarbitone anaesthesia in rabbits.
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