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Abstract
Dehghani, F., Panjehshahin, M.R., Mirzaee, Z. and Mehrabani, D. 2005. Effect of Foeniculum vulgare organic extract on blood sex hormones and reproductive tissues of male rats. J. Appl. Anim. Res., 27: 17–20.
To determine the effect of F. vulgare on reproductive system in male rats, forty male Sprague-Drawly rats were randomly placed in 4 equal groups. The control group received water and the remaining groups received 100, 250 and 500 mg/kg of organic extract of F. vulgare for 30 days. The animals were bled before and after medications and the blood, estrogen and testosterone levels were recorded. On day 30, the rats were sacrificed and dissected for histopathological study. Increase in the dose of F. vulgare administered to male rats resulted in a significant increase in estradiol and decrease in testosterone serum levels. Spermatocyte change from spherical to fussy form shape was visible in seminiferous tubules. Many nuclei in these cells were in metaphase stage. In higher doses of F. vulgare, hyalinizations of the tubules were also observed. It appears that F. vulgare can induce inhibitory effects on spermatogenic lineage in male rats.
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