Effect of Centrally Administered Sphingomyelin on Food Intake and HPA Axis in Chicks

F. Emoto Laboratory of Advanced Animal and Marine Bioresources, Graduate School of Bioresource and Bioenvironmental Sciences Kyushu University, Fukuoka, Japan

S. Tomonaga Laboratory of Advanced Animal and Marine Bioresources, Graduate School of Bioresource and Bioenvironmental Sciences Kyushu University, Fukuoka, Japan

T. Tachibana Laboratory of Advanced Animal and Marine Bioresources, Graduate School of Bioresource and Bioenvironmental Sciences Kyushu University, Fukuoka, Japan

D. M. Denbow Department of Animal and Poultry Sciences, Virginia Polytechnic Institute and State University, Blacksburg, VA, 24061-0306, USA

M. Furuse Laboratory of Advanced Animal and Marine Bioresources, Graduate School of Bioresource and Bioenvironmental Sciences Kyushu University, Fukuoka, Japan

Abstract

Emoto, F., Tomonaga, S., Tachibana, T., Denbow, D.M. and Furuse, M. 2006. Effect of centrally administered sphingomyelin on food intake and HPA axis in chicks. J. Appl. Anim. Res., 29: 91–96.

Sphignomyelin (SM) is an abundant lipid in myelin and its metabolites are well recognized as bioactive substances. The aim of the present study was to investigate the functions of SM in the chick brain. Intracerebroventricular (ICV) injection of SM decreased food intake in chicks. No significant changes in plasma corticosterone, glucose, 5-hydroxytryptamine and 5-hydroxyindoleacetic acid were detected. Thus anorexia caused by SM injection could be established but its mechanism could not be elucidated.

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Effect of Centrally Administered Sphingomyelin on Food Intake and HPA Axis in Chicks

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Effect of Centrally Administered Sphingomyelin on Food Intake and HPA Axis in Chicks

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