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Abstract
Emami M.J., Oryan, A., Meimandi-Parizi, A.M., Kasraee, R., Tanideh, N. and Mehrabani, D. 2006. Bone marrow transplantation and autogenic cancellous bone grafting in healing of segmental radial defects: an animal study. J. Appl. Anim. Res., 30: 69–72.
To compare the healing effect of bone marrow (BM) injection with the effects of autogenic cancellous bone graft (ABG), eighteen female and male New Zealand White rabbits (1 year, 2 kg) were randomly divided into three equal groups and osteotomy and extraction of a 5 mm piece of bone was done in the mid-portion of the right radius of all rabbits. In group A, 2 ml of BM was injected in the proximal femur for five consecutive days. Group B received autogenic cancellous bone graft from ileum and group C was the control group and received no intervention. After 45 days, in group A, 83% and 17% of rabbits showed good and medium healings, respectively, while in group B, 40% showed good and 60% medium healings. In control group, medium healing was 17% and poor healing was 83%. The mean healing score was significantly higher in BM injection group, compared with B and C groups (17.1, 15.2 and 6, respectively; P<0.05). BM injection could increase the quality of healing and was much more effective than bone grafting.