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Abstract
Gholami, S., Jelodar, G. and Alborzinia, H. 2008. Effect of hCG on rat endometrium at preimplantation stage. J. Appl. Anim. Res., 33: 89–92.
To compare histological changes in the endometrium of non pregnant, pregnant, pseudopregenant and hCG treated rat at preimplantation stage, twenty mature female rats at estrus stage were randomly divided in four groups of non pregnant (negative control), pregnant (positive control), pseudopregnant and treatment (hCG treated). Pseudopregnant and control positive groups were caged with vasectomised and intact male rat; respectively, while, control negative and test groups were not mated. Test group received hCG (10 IU) subcutaneously on second day of estrous cycle. On day 4 of estrous cycle (expected day of implantation) their uteri were subjected to histological study. There were changes in endometrial epithelium, glands and stromal cells in pseudopregnant and treatment groups, which were very similar to pregnant group. In conclusion hCG exerted moderate endometrial changes and may have potential value to improve pregnancy rate post embryo transfer.
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