Abstract
The ABO blood group distribution varies in different geographical and ethnic groups. In Punjab (India), the ABOblood frequency is B>O>A>AB. The current study was an attempt to correlate the ABO blood group frequency with preponderanceof breast and gastrointestinal cancer in Punjab, to assess the utility of ABO blood group as a preclinical marker. The study sampleconsists of 160 cancer patients and 160 controls. In cancer patients, the incidence of A and B groups was significantly highercompared to controls. In breast cancer, the frequency of A group was significantly higher and in oesophageal cancer, the frequencyof B group was significantly higher. The results indicate that blood type should be considered along with other risk factors tounderstand the individual patient’s risk.