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Abstract:
The aim of this study to determine the antimicrobial activitiy of essential oil of Ballota saxatilis subsp. brachyodonta (Boiss) P.H. Davis & Doroszenko. The oil was screened against human pathogenic seven bacteria and two yeast. Essential oil (EO) of B. saxatilis subsp. brachyodonta extracted by hidrodistilation, were analyzed by gas chromatography mass spectrometry (GC-MS). The main components of EO of B. saxatilis subsp. brachyodonta were caryophyllene (23.94 %), epi-bicyclosesquiphellandrene (20.20 %), caryophyllene oxide (10.50 %). Antimicrobial activity of essential oil (EO) of B. saxatilis subsp. brachyodonta was determined by using macro dilution method. All microorganisms except for Bacillus subtilis demonstrated some degree sensitivity to EO of B. saxatilis subsp. brachyodonta. Minimum inhibitory concentration (MIC) values have been changed in the range of 25-50 µg/ml. Essential oil of B. saxatilis subsp. brachyodonta possesses compounds with antimicrobial effect agains pathogen microorganisms.