Chemical Composition, Antibacterial and Antifungal Activities of the Leaf Essential Oil of Afraegle paniculata (Schumach. & Thonn.) Engl.

Moses S. Owolabi1 Department of Chemistry, Natural Products Research Unit, Faculty of Science, Lagos State University, Badagry-Expressway, P.M.B. 0001 LASU Post Office, Ojo, Lagos, NigeriaCorrespondence[email protected]

Akintayo L. Ogundajo1 Department of Chemistry, Natural Products Research Unit, Faculty of Science, Lagos State University, Badagry-Expressway, P.M.B. 0001 LASU Post Office, Ojo, Lagos, Nigeria

Tolulope Ewekeye2 Department of Botany Faculty of Science, Lagos State University, Badagry-Expressway, P.M.B. 0001 LASU Post Office, Ojo, Lagos, Nigeria

Olubunmi J. Sharaibi2 Department of Botany Faculty of Science, Lagos State University, Badagry-Expressway, P.M.B. 0001 LASU Post Office, Ojo, Lagos, Nigeria

Noura S. Dosoky3 Aromatic Plant Research Center, 230 N 1200 E, Suite 100, Lehi, UT84043, USA

William N. Setzer3 Aromatic Plant Research Center, 230 N 1200 E, Suite 100, Lehi, UT84043, USA;4 Department of Chemistry, University of Alabama in Huntsville, Huntsville, AL35803, USACorrespondence[email protected]

https://orcid.org/0000-0002-3639-0528

Abstract

Leaves of Afraegle paniculata were collected from southwestern Nigeria and hydrodistilled to give an essential oil in 0.56 % yield. The essential oil was analyzed by gas chromatography-mass spectrometry and was dominated by sesquiterpenoids. The major components in the leaf essential oil were α-copaene (20.1 %), (E)-caryophyllene (15.8 %), δ-cadinene (17.7 %) and caryophyllene oxide (18.4 %). The essential oil was screened for antimicrobial effects but showed only marginal activity (MIC ≥ 156 μg/mL).

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Chemical Composition, Antibacterial and Antifungal Activities of the Leaf Essential Oil of Afraegle paniculata (Schumach. & Thonn.) Engl.

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Chemical Composition, Antibacterial and Antifungal Activities of the Leaf Essential Oil of Afraegle paniculata (Schumach. & Thonn.) Engl.

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