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Abstract
The chemical constituents and antimicrobial activities of essential oils isolated from the leaf and stem of Piper albispicum C. DC. were reported. The main compounds of the leaf essential oil were chavicol acetate (16.3%), bicyclogermacrene (13.8%), sabinene (8.6%), b-pinene (7.7%) and a-pinene (7.3%). On the other hand b-pinene (15.6%), a-pinene (14.6%) and bicyclogermacrene (13.2%) were the significant compounds of the stem essential oil. The leaf oil displayed the best antimicrobial activity towards Pseudomonas aeruginosa ATCC27853 with the Minimum inhibitory concentration (MIC) value of 5.82 µg/mL. Both essential oils exhibited similar activities against Enterococcus faecalis ATCC299212 (MIC’s, 9.07 µg/mL and 9.81 µg/mL, respectively) and Candida albicans ATCC 10231 (MIC’s, 10.66 µg/mL and 10.91 µg/mL, respectively). However, the stem oil exhibited pronounced activity against Staphylococcus aureus ATCC25923 and Bacillus cereus ATCC14579, with MIC values of 10.22 µg/mL and 10. 44 µg/mL, respectively. However, the studied essential oils did not inhibit the growth of Escherichia coli ATCC 25922 and Salmonella enterica ATCC13076. This is the first report on the chemical constituents and antimicrobial activity of the essential oil of P. albispicum.