Pansinusitis in an HIV-infected patient due to Scedosporium apiospermum (Pseudallescheria boydii complex)

C KenyonDivision of Infectious Diseases and HIV Medicine, Department of Medicine, GF Jooste Hospital E-mail: [email protected]

M MendelsonDivision of Infectious Diseases and HIV Medicine, Department of Medicine, University of Cape Town

D LubbeDivision of Ear, Nose and Throat Surgery, Department of Surgery, University of Cape Town

B KhouryBrian Khoury, Department of Radiology Groote Schuur Hospital, Cape Town

H VismerHester Vismer, Medical Research Council, PROMEC Unit, Tygerberg

R HoffmanDepartment of Microbiology, National Health Laboratory Service, Groote Schuur Hospital, Cape Town

Abstract

Pseudallescheria boydii is a very rare cause of sinusitis but an increasingly recognised infection among HIV-infected patients. Its correct identifcation is vital as voriconazole, which has good in vitro activity against the fungus, has important interactions with antiretroviral drugs. We report the successful treatment of Scedosporium apiospermum pansinusitis, in an HIV-infected woman, which required alteration of antiretroviral therapy.

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Pansinusitis in an HIV-infected patient due to Scedosporium apiospermum (Pseudallescheria boydii complex)

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Pansinusitis in an HIV-infected patient due to Scedosporium apiospermum (Pseudallescheria boydii complex)

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