Inherited factor XI deficiency: A concise review

Abstract

Inherited factor XI (FXI) deficiency, also called Hemophilia C, is an uncommon autosomal recessive disorder, which is associated with a variable bleeding tendency that usually manifests after trauma or surgery. This concise report reviews current knowledge regarding the pathogenesis, genetics, diagnosis, clinical manifestations and management of this inherited bleeding disorder.

Keywords:

• FACTOR XI DEFICIENCY
• DESMOPRESSIN
• BLEEDING
• GENETICS