Microangiopathic Hemolytic Anemia Associated with the use of both Cyclosporin A and FK506 (Tacrolimus) in the Same Patient

Abstract

Microangiopathic hemolytic anemia (MAHA) is a well recognized complication of cyclosporin A (CyA) immunosupressive therapy post bone marrow and solid organ transplant but has rarely been reported in association with FK506 (tacrolimus), we describe a unique patient in whom both CyA and FK506 appear to have caused microangiopathy following an allogeneic peripheral stem cell transplant.

Keywords:

• Microangiopathic hernolytic anemia
• allogeneic transplant
• cyclosporin A
• tacrolimus
• FK506