Current Management in Sickle Cell Disease

Abstract

The number of people in the UK with sickle cell disease continues to rise. Therefore it becomes increasingly important for all clinicians to be cognisant of not only the disorder, but also its complications, prognosis, implications and management. Previously the majority of patients lived within urban areas and attended a few specialist centres, now the young, mobile population of patients are no longer confined to teaching hospitals. In the UK, few centres have experience of many patients but collectively patients' numbers are considerable. This review discusses our view of the current management of the acute and chronic manifestations of this disease, supplemented by international advances, anecdote and current research.

Keywords:

• Sickle cell disease
• acute and chronic complications
• novel therapies