Abstract
The study subjects were 192 overweight and obese Thais (BMI > 25.00 kg/m 2 ), and 103 Thai controls (BMI = 18.50–24.99 kg/m 2 ), whose ages ranged from 18–60 years. All subjects were evaluated for serum Alpha-2-macroglobulin (A 2 M), globulin, albumin concentration, and polymorphic variation in the A 2 M gene. Serum A 2 M and albumin were significantly lower in the overweight/obese group ( P