Three polyoxygenated cyclohexenes from Uvaria calamistrata

Abstract

Three new polyoxygenated cyclohexenes, named uvacanols F, G, H (1–3), were isolated from the roots of Uvaria calamistrata (Annonaceae). Their structures were determined to be 2-acetoxyl-5-chlorine-benzoyloxymethylcyclohex-1 (6)-ene-4-ol-3-benzoate (1), benzoyloxy-methylcyclohex-1 (6)-ene-2,3,4-triols-5-benzoate (2), 3-acetoxyl-benzoyloxymethylcyclohex-1 (6)-ene-4,5-diols-2-benzoate (3) by spectroscopic methods and chemical derivatization.

Keywords:

• Annonaceae
• Uvaria calamistrata
• polyoxygenated cyclohexenes
• uvacanols F, G, H

Acknowledgements

We would like to thank Mr Si-Man Huang at the Center of Life Science, Hainan University for the collection of the plant material. HR-ESI-MS were measured at the Institute of Traditional Medicine and Natural Products, College of Pharmacy, Jinan University.