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Abstract
Two new isoprenylated flavonoids, artotonins A and B (1 and 2), along with 13 known compounds (3–15), were isolated from the roots of Artocarpus tonkinensis A. Chev. ex Gagnep. The structures were elucidated by spectroscopic methods. Cyclocommunol (6), isocyclomulberrin (7), cudraflavone C (11), and morusin (13) exhibited cytotoxicity against hepatocellular carcinoma (SMMC-7721) and gastric carcinoma (BGC-823 and SGC-7901) cell lines.
Acknowledgement
This study was financially supported by the National Natural Science Foundation of China (30572247) and the Key National Scientific and Technological Program ‘Major New Drug Development’ of the Ministry of Science and Technology of the PR China (No. 2009ZX09301-011).