Phenolic glycosides isolated from the bark of Lysidice brevicalyx Wei

Abstract

Two new compounds, lysidiside S (1) and 7-O-(+)-peltogynol-β-d-glucopyranoside (2), together with six known phenolic glycosides (3–8) were isolated from the bark of Lysidice brevicalyx Wei. The structures of these compounds were characterized by chemical and spectroscopic methods. The antioxidant activities of compounds 1–8 were evaluated, and compound 3 exhibited remarkable antioxidant activity at concentrations of 10^− 4, 10^− 5, and 10^− 6 mol/l.

Keywords:

• Lysidice brevicalyx
• lysidiside S
• 7-O-(+)-peltogynol-β-d-glucopyranoside
• antioxidant

Acknowledgements

The research project was supported by the National Fund for Distinguished Young Scholars (No. 30625040) and National Key Basic R&D (973) Project (No. 2004CB518906). We thank the Department of Medicinal Analysis, Institute of Materia Medica, Chinese Academy of Medical Sciences for the measurements of IR, NMR, and MS spectra, and the Department of Pharmacology of our institute for antioxidation tests.